IL7R anticorps (AA 21-236)
Aperçu rapide pour IL7R anticorps (AA 21-236) (ABIN6937563)
Antigène
Voir toutes IL7R AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 21-236
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Specificité
- The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID).
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Réactivité croisée (Details)
- Human.
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Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
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Immunogène
- Recombinant fragment (around aa 21-236) of human CD127 protein (IL7R) (exact sequence is proprietary)
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Isotype
- IgG2c kappa
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Indications d'application
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Known_Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: K562, HeLa, Daudi or Jurkat cells. Tonsil, Lymph Node or Spleen.
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Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
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Agent conservateur
- Azide free
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
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Date de péremption
- 24 months
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- IL7R (Interleukin 7 Receptor (IL7R))
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Autre désignation
- IL7R
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Sujet
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CD127, IL-7 receptor subunit alpha, IL-7R-alpha, IL7R, IL7RA, IL7R alpha, ILRA, Interleukin 7 receptor alpha chain, Interleukin 7 receptor,CD127 / IL7R (Marker of T-Reg Cells)
Cellular localisation: Cell Surface and Cytoplasmic -
Poids moléculaire
- 52-72kDa
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ID gène
- 3575, 591742, 635723
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UniProt
- P16871
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Pathways
- Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
Antigène
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